Peptide & Compound Guide
At a glance
| Compound | GHK-Cu |
|---|---|
| Type | Copper-binding tripeptide |
| U.S. regulatory context | Not an FDA-approved systemic peptide drug; cosmetic/topical uses are distinct from drug approval |
| Evidence level | Laboratory, topical and limited clinical research depending on use |
| Research area | Skin biology, wound research, extracellular matrix and cellular signaling |
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding tripeptide studied in skin and wound-related biology. It is also used as an ingredient in some cosmetic products, which should not be confused with approval as a therapeutic drug.
What does the research examine?
Research has examined signaling, collagen-related processes and tissue biology. Evidence strength depends heavily on formulation and route of use.
What has not been established?
Mechanism, biomarker changes, animal findings and early clinical signals are not the same as proof that a compound safely improves meaningful health outcomes. Claims should be matched to the type, size and quality of evidence available.
Safety and regulatory context
Claims for injectable or systemic anti-aging effects should not be inferred from cosmetic or laboratory research.
Research sources
Use primary and authoritative sources when evaluating claims about this compound. Search results can change as new research is published.